Patrick Casale

Patrick Casale

Keynote Speaker: Neurodivergent Workplace Strategist & Culture Creator; Burnout Prevention Expert; Co-Host of the "Divergent Conversations" Podcast & Author of "So You're Autistic...Now What?"

Patrick Casale Biography

Patrick Casale is a TEDx speaker, keynote presenter, consultant, and thought leader whose work explores late-in-life Autism discovery, leadership, workplace culture, and the often-hidden cost of self-doubt.

Casale’s TEDx talk on discovering Autism in adulthood stands as a defining moment in his speaking career. Through deeply personal storytelling and clinical insight, he illuminated what it means to grow up undiagnosed, to learn how to mask in order to survive, and to later untangle identity, burnout, and belonging as an adult. His talk resonated widely for its honesty and clarity—giving language to experiences many people had lived but never heard named.

As a speaker, Casale brings a rare combination of lived experience, professional expertise, and executive-level leadership. He delivers keynotes and trainings for conferences, organizations, and leadership teams across the U.S. and internationally, helping audiences rethink neurodivergence, productivity, and performance through a more humane and inclusive lens. His work challenges systems that reward over-functioning and quiet suffering, while offering practical pathways toward psychological safety, sustainable leadership, and neurodivergent-affirming cultures.

Casale is the host of two globally recognized podcasts, All Things Private Practice and Divergent Conversations, where he has facilitated hundreds of conversations on Autism, ADHD, identity, leadership, entrepreneurship, and mental health. Across these platforms, he has become a trusted voice for professionals and leaders navigating late diagnosis, burnout, and the tension between success and self-abandonment.

He is also the author of an upcoming book focused on late-in-life Autism discovery, identity reconstruction, and the emotional aftermath of finally understanding your nervous system after decades of misattunement. The book extends the core themes of his TEDx talk—grief, relief, self-doubt, and self-trust—while offering readers language, validation, and hope.

Casale’s speaking style is authentic, disarming, and story-driven. He blends vulnerability, humor, and insight to create spaces where people feel seen without being pathologized. Whether addressing clinicians, executives, entrepreneurs, or organizational leaders, his message is consistent: self-doubt is not a flaw, neurodivergence is not a deficit, and leadership begins when we stop forcing people—including ourselves—to perform inside systems that were never built for us.

Contact a speaker booking agent to check availability on Patrick Casale and other top speakers and celebrities.

Patrick Casale Speaking Topics

Doubt Yourself, Do It Anyway: Leading Through Fear, Uncertainty, and Change

Self-doubt, fear of failure, and uncertainty are not signs of weakness—they are natural companions to meaningful leadership and innovation. In this talk, Patrick Casale reframes doubt as a catalyst rather than an obstacle. Drawing from his experience as a therapist, entrepreneur, and speaker, he explores how leaders can take aligned risks, navigate discomfort, and make values-based decisions even when clarity is missing. This session challenges hustle culture and perfectionism while offering practical tools for moving forward without waiting for confidence to arrive. Attendees leave with a grounded framework for courageous leadership, sustainable momentum, and authentic impact—especially during times of rapid change and burnout.

Neurodiversity at Work: Building Inclusive, Human-Centered Organizations

Neurodivergent individuals (Autistic, ADHD, AuDHD, dyslexic, highly sensitive, and more) are deeply embedded in today’s workforce—often without adequate support or understanding. This session introduces a neurodiversity-affirming lens to leadership, culture, and workplace design. Patrick Casale explores common systemic barriers, the cost of masking and burnout, and how organizations can move beyond performative inclusion toward meaningful accessibility. Leaders will learn how to build environments that support diverse thinking styles, communication needs, and sensory differences—resulting in stronger retention, innovation, and psychological safety. This talk is ideal for organizations seeking to align values with action.

Beyond Burnout: Redefining Success Without Sacrificing Your Well-Being

Burnout is not a personal failure—it is often the result of misaligned systems, unrealistic expectations, and chronic over-functioning. In this session, Patrick Casale challenges traditional definitions of success that prioritize productivity over people. He explores the emotional, neurological, and cultural contributors to burnout and offers a compassionate, practical approach to sustainability. Attendees are guided through reframing boundaries, redefining ambition, and building work lives that honor capacity, nervous system health, and long-term fulfillment. This talk resonates deeply with helping professionals, leaders, and high-achievers who are outwardly successful but inwardly exhausted.

Late Identification & Identity: The Impact of Discovering Who You Really Are

Discovering one’s neurodivergent identity in adulthood can be both liberating and disorienting. This powerful and personal talk explores the emotional landscape of late identification—grief, relief, anger, clarity, and self-compassion. Patrick Casale shares insights from both lived experience and professional practice, highlighting how identity impacts leadership, communication, relationships, and self-trust. Attendees gain a deeper understanding of how late-discovered identities reshape narratives of success and self-worth, and how organizations and communities can better support individuals navigating these transitions with dignity and respect.

People Over Profit: Values-Based & Unorthodox Leadership Styles

In an era of constant growth pressure and shrinking margins, values-based leadership is often the first casualty. This session challenges the myth that sustainability and humanity are incompatible with success. Patrick Casale explores what it means to lead with integrity, transparency, and care—without abandoning ambition. Through real-world examples, he demonstrates how prioritizing people, accessibility, and ethics leads to healthier teams, stronger cultures, and long-term resilience. This talk invites leaders to examine how their values show up in hiring, decision-making, communication, and growth—and how aligning actions with values creates trust, loyalty, and meaningful impact.

Patrick Casale Videos

Patrick Casale | TEDxManitouSprings

How do I book Patrick Casale to speak at my event?

Our experienced booking agents have successfully helped clients around the world secure speakers like Patrick Casale for speaking engagements, personal appearances, product endorsements, or corporate entertainment since 2002. Click the Check Schedule button above and complete the form on this page to check availability for Patrick Casale, or call our office at 1.800.698.2536 to discuss your upcoming event. One of our experienced agents will be happy to help you get speaking fee information and check availability for Patrick Casale or any other speaker of your choice.

How much does it cost to book Patrick Casale for a speaking engagement?

Speaking fees for Patrick Casale, or any other speakers and celebrities, are determined based on a number of factors and may change without notice. The estimated fees to book Patrick Casale are $10,000 - $20,000 for live events and $10,000 - $20,000 for virtual events. For the most current speaking fee to hire Patrick Casale, click the Check Schedule button above and complete the form on this page, or call our office at 1.800.698.2536 to speak directly with an experienced booking agent.

What topics does Patrick Casale speak about?

Patrick Casale is a keynote speaker and industry expert who speaks on a wide range of topics such as Neurodiversity, Belonging, Storytelling, Stress Management, Mental Health, Work-Life Balance, Business Leadership, Disability, DEI, Leadership, Success, Podcast Host, TED, Personal Growth, Human Resources and Author.

Where does Patrick Casale travel from?

Patrick Casale generally travels from Asheville, NC, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances.

Who is the agent for Patrick Casale?

AAE Speakers Bureau has successfully secured keynote speakers like Patrick Casale for clients worldwide since 2002. As a full-service speaker booking agency, we have access to virtually any speaker or celebrity in the world. Our agents are happy and able to submit an offer to the speaker or celebrity of your choice, letting you benefit from our reputation and long-standing relationships in the industry. Please click the Check Schedule button above and complete the form on this page including the details of your event, or call our office at 1.800.698.2536, and one of our agents will assist you to book Patrick Casale for your next private or corporate function.

What is a full-service speaker booking agency?

AAE Speakers Bureau is a full-service speaker booking agency, meaning we can completely manage the speaker’s or celebrity’s engagement with your organization from the time of booking your speaker through the event’s completion. We provide all of the services you need to host Patrick Casale or any other speaker of your choice, including offer negotiation, contractual assistance, accounting and billing, and event speaker travel and logistics services. When you book a speaker with us, we manage the process of hosting a speaker for you as an extension of your team. Our goal is to give our clients peace of mind and a best-in-class service experience when booking a speaker with us.

Why is AAE Speakers Bureau different from other booking agencies?

If you’re looking for the best speaker recommendations, paired with a top-notch customer service experience, you’re in the right place. At AAE Speakers Bureau, we exclusively represent the interests of our clients - professional organizations, companies, universities, and associations. We intentionally do not represent the speakers we feature or book. That is so we can present our clients with the broadest and best performing set of speaker options in the market today, and we can make these recommendations without any obligation to promote a specific speaker over another. This is why when our agents suggest a speaker for your event, you can be assured that they are of the highest quality with a history of proven success with our other clients.


Patrick Casale is a keynote speaker and industry expert who speaks on a wide range of topics including Neurodiversity, Belonging and Storytelling. The estimated speaking fee range to book Patrick Casale for live events is $10,000 - $20,000, and for virtual events $10,000 - $20,000. Patrick Casale generally travels from Asheville, NC, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances. Similar motivational celebrity speakers are Elena Agaragimova, Adam Markel and Matt Johnson. Contact All American Speakers for ratings, reviews, videos and information on scheduling Patrick Casale for an upcoming event.

Speaker profile last updated by AAE Talent Team on 13/01/2026.

Patrick Casale Speaking Topics

  • Doubt Yourself, Do It Anyway: Leading Through Fear, Uncertainty, and Change

    Self-doubt, fear of failure, and uncertainty are not signs of weakness—they are natural companions to meaningful leadership and innovation. In this talk, Patrick Casale reframes doubt as a catalyst rather than an obstacle. Drawing from his experience as a therapist, entrepreneur, and speaker, he explores how leaders can take aligned risks, navigate discomfort, and make values-based decisions even when clarity is missing. This session challenges hustle culture and perfectionism while offering practical tools for moving forward without waiting for confidence to arrive. Attendees leave with a grounded framework for courageous leadership, sustainable momentum, and authentic impact—especially during times of rapid change and burnout.

  • Neurodiversity at Work: Building Inclusive, Human-Centered Organizations

    Neurodivergent individuals (Autistic, ADHD, AuDHD, dyslexic, highly sensitive, and more) are deeply embedded in today’s workforce—often without adequate support or understanding. This session introduces a neurodiversity-affirming lens to leadership, culture, and workplace design. Patrick Casale explores common systemic barriers, the cost of masking and burnout, and how organizations can move beyond performative inclusion toward meaningful accessibility. Leaders will learn how to build environments that support diverse thinking styles, communication needs, and sensory differences—resulting in stronger retention, innovation, and psychological safety. This talk is ideal for organizations seeking to align values with action.

  • Beyond Burnout: Redefining Success Without Sacrificing Your Well-Being

    Burnout is not a personal failure—it is often the result of misaligned systems, unrealistic expectations, and chronic over-functioning. In this session, Patrick Casale challenges traditional definitions of success that prioritize productivity over people. He explores the emotional, neurological, and cultural contributors to burnout and offers a compassionate, practical approach to sustainability. Attendees are guided through reframing boundaries, redefining ambition, and building work lives that honor capacity, nervous system health, and long-term fulfillment. This talk resonates deeply with helping professionals, leaders, and high-achievers who are outwardly successful but inwardly exhausted.

  • Late Identification & Identity: The Impact of Discovering Who You Really Are

    Discovering one’s neurodivergent identity in adulthood can be both liberating and disorienting. This powerful and personal talk explores the emotional landscape of late identification—grief, relief, anger, clarity, and self-compassion. Patrick Casale shares insights from both lived experience and professional practice, highlighting how identity impacts leadership, communication, relationships, and self-trust. Attendees gain a deeper understanding of how late-discovered identities reshape narratives of success and self-worth, and how organizations and communities can better support individuals navigating these transitions with dignity and respect.

  • People Over Profit: Values-Based & Unorthodox Leadership Styles

    In an era of constant growth pressure and shrinking margins, values-based leadership is often the first casualty. This session challenges the myth that sustainability and humanity are incompatible with success. Patrick Casale explores what it means to lead with integrity, transparency, and care—without abandoning ambition. Through real-world examples, he demonstrates how prioritizing people, accessibility, and ethics leads to healthier teams, stronger cultures, and long-term resilience. This talk invites leaders to examine how their values show up in hiring, decision-making, communication, and growth—and how aligning actions with values creates trust, loyalty, and meaningful impact.

Patrick Casale Videos

Patrick Casale | TEDxManitouSprings
  • How do I book Patrick Casale to speak at my event?

    Our experienced booking agents have successfully helped clients around the world secure speakers like Patrick Casale for speaking engagements, personal appearances, product endorsements, or corporate entertainment since 2002. Click the Check Schedule button above and complete the form on this page to check availability for Patrick Casale, or call our office at 1.800.698.2536 to discuss your upcoming event. One of our experienced agents will be happy to help you get speaking fee information and check availability for Patrick Casale or any other speaker of your choice.
  • How much does it cost to book Patrick Casale for a speaking engagement?

    Speaking fees for Patrick Casale, or any other speakers and celebrities, are determined based on a number of factors and may change without notice. The estimated fees to book Patrick Casale are $10,000 - $20,000 for live events and $10,000 - $20,000 for virtual events. For the most current speaking fee to hire Patrick Casale, click the Check Schedule button above and complete the form on this page, or call our office at 1.800.698.2536 to speak directly with an experienced booking agent.
  • What topics does Patrick Casale speak about?

    Patrick Casale is a keynote speaker and industry expert who speaks on a wide range of topics such as Neurodiversity, Belonging, Storytelling, Stress Management, Mental Health, Work-Life Balance, Business Leadership, Disability, DEI, Leadership, Success, Podcast Host, TED, Personal Growth, Human Resources and Author.
  • Where does Patrick Casale travel from?

    Patrick Casale generally travels from Asheville, NC, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances.
  • Who is the agent for Patrick Casale?

    AAE Speakers Bureau has successfully secured keynote speakers like Patrick Casale for clients worldwide since 2002. As a full-service speaker booking agency, we have access to virtually any speaker or celebrity in the world. Our agents are happy and able to submit an offer to the speaker or celebrity of your choice, letting you benefit from our reputation and long-standing relationships in the industry. Please click the Check Schedule button above and complete the form on this page including the details of your event, or call our office at 1.800.698.2536, and one of our agents will assist you to book Patrick Casale for your next private or corporate function.
  • What is a full-service speaker booking agency?

    AAE Speakers Bureau is a full-service speaker booking agency, meaning we can completely manage the speaker’s or celebrity’s engagement with your organization from the time of booking your speaker through the event’s completion. We provide all of the services you need to host Patrick Casale or any other speaker of your choice, including offer negotiation, contractual assistance, accounting and billing, and event speaker travel and logistics services. When you book a speaker with us, we manage the process of hosting a speaker for you as an extension of your team. Our goal is to give our clients peace of mind and a best-in-class service experience when booking a speaker with us.
  • Why is AAE Speakers Bureau different from other booking agencies?

    If you’re looking for the best speaker recommendations, paired with a top-notch customer service experience, you’re in the right place. At AAE Speakers Bureau, we exclusively represent the interests of our clients - professional organizations, companies, universities, and associations. We intentionally do not represent the speakers we feature or book. That is so we can present our clients with the broadest and best performing set of speaker options in the market today, and we can make these recommendations without any obligation to promote a specific speaker over another. This is why when our agents suggest a speaker for your event, you can be assured that they are of the highest quality with a history of proven success with our other clients.
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