Before AI went mainstream, Andrew Mayne was an outsider—an author and magician exploring the edges of human creativity. That same curiosity led him inside OpenAI, where he became the company’s first prompt engineer and helped shape the way humans and machines think together. In this talk, he shares lessons from inside one of the world’s most influential AI labs: how to recognize inflection points before they happen, turn uncertainty into momentum, and build a career that thrives through technological upheaval. It’s a roadmap for anyone, from executives to creators, who wants to navigate the AI revolution not as a passenger, but as a pilot.
A decade ago, Andrew Mayne bet his career on artificial intelligence—and watched it evolve from a lab curiosity into the defining force of our time. From the inside of OpenAI to the frontlines of startup innovation, he has seen how quickly the future arrives and who actually captures its value. In this talk, he offers a grounded look at where AI is going next—what’s real, what’s noise, and what leaders need to prepare for now. It’s an insider’s guide to navigating the next wave of intelligence, from models to markets to mindsets.
From OpenAI to Interdimensional, Andrew Mayne has seen firsthand what separates companies that talk about AI from those that win with it. This session reveals how to build and lead teams that amplify human capability with intelligent tools—where small, focused groups can out-innovate entire industries. He breaks down the playbook for assembling AI-literate teams, integrating models into real workflows, and fostering a culture where experimentation drives measurable growth.
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